To the best of our knowledge humans are the only species that does Mathematics. There have been many attempts to prove if any other being (animal or plant) can perform this task but none of which showed positive results. The most famous of these stories is that of ‘clever Hans’ a story of a horse that could perform Mathematics well at least his owner thought so and upon analysis was found that the owner without his conscious knowledge was giving signals to the horse. Using several brain imaging techniques we can have a better picture of how the brain reacts while we perform

•          Complex calculation in our mind

•          Imagine a polyhedron

•          Solve a long derivation

•          Prove a theorem

And all these would have different representations in our brain. A better approach to find it would be to use data mining and other tools to understand the implications of an increasing wealth of DNA and genomic information for brain chemistry.